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biologics inc ultrasonic homogenizers antibiotic potency testing systems automated bacterial colony counters the most reliable life science instrumentation for the highest performance and accuracy product catalog 2010

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contents ultrasonic homogenizers ultrasonic homogenizers model 150vt 300vt ultrasonic homogenizers model 3000 ultrasonic homogenizers small volume accessories ultrasonic homogenizers medium to large volume accessories ultrasonic homogenizers medium to large volume accessories continued ultrasonic homogenizers cup tip ultrasonic homogenizers continuous flow chamber ultrasonic homogenizers sound abating chamber omnicon potency testing system omnicon zone reader 100mm petri dishes specifications omnicon large plate zone reader 250mm and 340mm square plates specifications omni-noculator automated peni cylinder filler omni-noculator automated peni cylinder filler specifications peni cylinder dispensers manual peni cylinder dispenser peni cylinder dispenser with hoppper peni cylinder dispenser with motorized hopper peni cylinders automated bacterial colony counter automated bacterial colony counter specifications automated bacterial colony counter how it works ordering and payment terms warranty 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 navigation you will find the following navigation icons throughout the catalog to return to the catalog contents page click this icon to be directed to the online application notes or published papers click this icon to be directed to our online shopping cart click this icon www.biologics-inc.com contents and navigation 2

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01 ultrasonic homogenizers advanced instrumentation with built in high performance and convenience our ultrasonic homogenizers offer precision engineering with all the features necessary to create a total system for ultrasonic disruption it can disintegrate most cells bacteria spores or tissue it can prepare an emulsion down to 1/100 of a micron homogenize immiscible liquids accelerate enzymatic and chemical reactions stimulate bacterial activity disperse solids in liquids and degas liquids how it works the ultrasonic power supply transforms line voltage to high frequency 20 khz of electrical energy this electrical energy is transmitted to the probe where it is changed to mechanical energy the vibrations from the probe are coupled to and intensified by the titanium tip the probe vibrates in a longitudinal direction and transmits this motion to the titanium tip immersed in the solution cavitation results in which microscopic vapor bubbles are formed momentarily and implode causing powerful infinitesimal shock waves to radiate throughout the solution in proximity to the radiating face of the tip automatic tuning our ultrasonic homogenizers employ a proprietary feedback system insuring that the ultrasonic homogenizer is always working at its maximum efficiency regardless of the application there is no need for constant adjustment by the operator the percentage of ultrasonic power emitted is indicated by the output meter enabling accurate reproducible results performance the ultrasonic generators provide continuous duty operation on difficult or large scale applications www.ultrasonichomogenizer.com ultrasonic homogenizers 3

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ultrasonic homogenizers model 150vt and model 300vt model 150vt catalog no voltage 0-121-0001 0-121-0002 features 115 volts/60hz 230 volts/50hz titanium tips purchased separately power output output frequency automatic tuning microprocessor control duty cycle pulsing timer display sound abating chamber dimensions 0 150 watts 20k hz yes n/a 10 90 1 15 minutes led optional generator transducer 12.0 in w x 10.0 in d x 4.0 in h 30.5 cm w x 25.4 cm d x 10.2 cm h 3.5 in dia x 4.0 in l 8.9 cm dia x 10.2 cm l shown with optional 5/32 3.9mm diameter titanium stepped micro tip model 300vt catalog no voltage 0-122-0001 0-122-0002 features 115 volts/60hz 230 volts/50hz titanium tips purchased separately power output output frequency automatic tuning microprocessor control duty cycle pulsing timer display sound abating chamber dimensions 0 300 watts 20k hz yes n/a 10 90 1 15 minutes led optional generator transducer 12.0 in w x 10.0 in d x 4.0 in h 30.5 cm w x 25.4 cm d x 10.2 cm h 3.5 in dia x 4.0 in l 8.9 cm dia x 10.2 cm l shown with optional 1/2 12.7mm diameter solid titanium tip www.ultrasonichomogenizer.com ultrasonic homogenizers 4

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ultrasonic homogenizers model 3000 model 3000 catalog no voltage 0-127-0001 0-127-0002 features 115 volts/60hz 230 volts/50hz titanium tips purchased separately power output output frequency automatic tuning microprocessor control duty cycle pulsing timer meter type sound abating chamber dimensions 0 300 watts 20k hz yes n/a 10 90 1 15 minutes led integrated generator transducer 10.5 in w x 12.0 in d x 23.5 in h 26.7 cm w x 30.5 cm d x 59.7 cm h 3.5 in dia x 4.0 in l 8.9 cm dia x 10.2 cm l shown with optional 1/2 12.7mm diameter solid titanium tip www.ultrasonichomogenizer.com ultrasonic homogenizers 5

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ultrasonic homogenizers small volume accessories titanium micro tips micro horns catalog no 0-120-0005 tip diameter processing vol intensity amplitude type 5/32 3.8 mm 300 µl 15 ml very high 225 µm stepped 1/8 3.2 mm dia tapered micro tip shown attached to 1/2 12.7 mm dia tapped tip catalog no tip diameter processing vol intensity amplitude type 0-120-0007 1/8 3.1 mm 500 µl 10 ml very high 240 µm tapered 0-120-0008 3/16 4.8 mm 750 µl 25 ml high 200 µm tapered 2 piece design and must be used in conjunction with the 1/2 dia tapped tip cat no 0-120-0010 www.ultrasonichomogenizer.com ultrasonic homogenizers 6

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ultrasonic homogenizers medium to large volume accessories titanium standard tips horns the terms tip and horn are interchangeable typically as the tip diameter decreases the intensity or amplitude of the radiating face increases as does the overall length catalog no 0-120-0009 tip diameter processing vol intensity amplitude type 3/8 9.2 mm 5 ml 200 ml high 170 µm solid 0-120-0010 1/2 12.7 mm 10 ml 300 ml medium high 140 µm tapped 0-120-0011 1/2 12.7 mm 10 ml 300 ml medium high 140 µm solid catalog no tip diameter processing vol intensity amplitude type 0-120-0012 3/4 19.1 mm 25 ml 600 ml medium 70 µm tapped 0-120-0013 3/4 19.1 mm 25 ml 600 ml medium 70 µm solid sold tips solid tips are machined from a single piece of titanium and are preferred when processing liquids with high surface tension in addition solid tips are generally less likely to cause sample cross contaminations catalog no tip diameter processing vol intensity amplitude type 0-120-0014 1 25.4 mm 50 ml 1000 ml low 40 µm tapped 0-120-0015 1 25.4 mm 50 ml 1000 ml low 40 µm solid tapped tips all tapped tips include 1 titanium replacement flat tip flat tips should be replaced when they show signs of excessive pitting and intensity/performance is greatly decreased includes 1 titanium replaceable flat tip www.ultrasonichomogenizer.com ultrasonic homogenizers 7

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ultrasonic homogenizers medium to large volume accessories continued titanium replacement flat tips catalog no 0-120-0016 0-120-0017 0-120-0018 tip diameter 1/2 12.7 mm 3/4 19.1 mm 1 25.4 mm 3/4 19.1 mm dia replacement flat tip shown attached to 3/4 19.1 mm dia tapped tip www.ultrasonichomogenizer.com ultrasonic homogenizers 8

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ultrasonic homogenizers cup tips and accessories titanium cup tips the titanium cup tips provide an easy way to process samples without direct exposure to the homogenizer tip avoiding cross contamination titanium cup tips can simultaneously process sealed vial test tubes or micro tubes with identical parameters 250 ml cup tip and 8 position micro tube tray shown attached to transducer assembly catalog no tip diameter processing vol intensity 0-120-0019 1 1/2 38.1 mm 250 ml medium 0-120-0020 2 50.8 mm 2000 ml low must be powered by the model 300vt or 3000 only micro tube tray holders catalog no 0-120-0019 0-120-0020 no of tubes 8 20 if cooling is required with heat sensitive samples cold water can be fed through the cup tip using the provided barbed fittings the cup tip can also be used without the cooling feature by simply using the provided port plugs in place of the barbed fittings www.ultrasonichomogenizer.com ultrasonic homogenizers 9

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ultrasonic homogenizers continuous flow chamber this chamber permits continuous processing of liquids and is designed for emulsifying and homogenizing applications the continuous flow chamber may be sealed in a closed system when mounted so that infectious materials can be used it is equipped with a water flow-through cooling jacket to enable the temperature of the processed solution to be maintained at a desired level catalog no 0-120-0026 continuous flow chamber requires the 3/4 19.1 mm diameter solid titanium tip catalog no 0-120-0013 continuous flow chamber shown with 3/4 dia solid titanium tip and transducer assembly 2 cooling jacket ports 3 sample port www.ultrasonichomogenizer.com ultrasonic homogenizers 10

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ultrasonic homogenizers sonabox sound abating chamber sonabox the sonabox reduces cavitational sound emitted during processing when used in conjunction with the model 150vt and 300 vt ultrasonic homogenizer these harmonics are produced by the vessel walls and fluid surface and can be disturbing with extended operation the clear acrylic door permits viewing of the sample while protecting the operator against accidental splashing an access port for tubing is also provided for use with the accessory cooling jacket or continuous flow chamber transducer compartment catalog no 0-125-0001 sonabox sound abating chamber adjustable sample table transparent sample door www.ultrasonichomogenizer.com ultrasonic homogenizers 11

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02 omnicon® antibiotic potency testing now you can get fast reproducible quantitative results while you automate one of the most time consuming tedious tasks in your lab put an omnicon® zone reader system to work for you no matter what your volume of zones assays no matter what your budget either of the omnicon® zone reader systems will suit your needs the omnicon® zone reader systems integrates image analysis comparison and reporting to provide accurate results in record time the omnicon zone reader performs the following multi-plate assays 100 mm round petri dish · united states pharmacopeia usp method · british pharmacopeia bp european pharmacopeia ep method · japanese pharmcopeia method jp the omnicon large plate zone reader performs the following latin square assays 240 mm or 355 mm square dish · british pharmacopeia bp method · european pharmacopeia ep method all omnicon® zones of inhibition software are 21 cfr part 11 electronic records and signature compliant providing three levels of security audit trails and data file protection the omnicon® zone of inhibition software is easy to use and includes these features · calculations performed automatically · predefined and user defined assay/product protocols · user defined reports and graphs · outlier test the omnicon® zone reader systems are affordable it is a solid investment that will quickly pay off with improved efficiency accuracy and increased productivity there is no better faster or more economical way to analyze antibiotic potency than the omnicon® zone reader systems www.omniconzonereader.com omnicon antibiotic pentency tesing 12

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omnicon® antibiotic potency testing multi plate assay 100 mm petri dishes omnicon zone reader 100mm round petri dishes measuring zone diameters on 100 mm round petri dishes has never been easier using the omnicon zone reader you can get fast reproducible quantitative antibiotic potency results while automating one of the most timeconsuming tedious tasks in your lab the software enables automatic zone diameter measuring applies the usp outlier test or gap test performs all calculation based on percent label claim or weight and dilution regardless of the agar diffusion method being used peni cylinders cut wells or paper disc the omnicon zone reader analyzes them all effortlessly the omnicon zones of inhibition software is 21 cfr part 11 electronic records and signature compliant and provides three levels of security encrypted data files and comprehensive audit trails catalog no voltage 0-131-0001 0-131-0002 features 115 volts/60hz 230 volts/50hz software environment pharmacopeia methods cfr part 11 ers plate size pc illumination camera dimensions windowstm us ep/bp jp and 2+2 compliant 100 mm round petri dish integrated intel dual core reflected and transmitted high resolution b/w main unit 10.0 in w x 24.0 in d x 14.0 in h 25.4 cm w x 60.9 cm d x 35.6 cm h www.omniconzonereader.com omnicon antibiotic pentency tesing 13

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omnicon® antibiotic potency testing large plate latin square omnicon large plate zone reader 240 mm or 355mm square dishes the omnicon large plate zone reader integrates image analysis automatic stage comparison and reporting to provide accurate results in record time the automatic motorized scanning stage can accommodate either a 240 mm or 355 mm square dish the omnicon large plate zones reader can measure all zones on a 240 mm square plate calculate results display and print results in 2-3 minutes the large plate omnicon zones of inhibition software is 21 cfr part 11 electronic records and signature compliant and provides three levels of security encrypted data files and comprehensive audit trails catalog no voltage 0-132-0001 0-132-0002 features 115 volts/60hz 230 volts/50hz software environment pharmacopeia methods cfr part 11 ers plate size stage pc illumination camera dimensions windowstm ep/bp compliant 240 mm or 355 mm square automatic motorized integrated intel dual core transmitted or reflected high resolution b/w main unit 10.0 in w x 24.0 in d x 14.0 in h 25.4 cm w x 60.9 cm d x 35.6 cm h www.omniconzonereader.com omnicon antibiotic pentency tesing 14

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03 omni-noculator peni cylinder filler the omni-noculator is a robotic liquid handling system designed to fill peni cylinders with the corresponding antibiotic sample the analyst defines the pharmacopeia method usp ep/bp or jp the number of plates to replicate or number of plates within the assay selects one of several dispense patterns and the volume of antibiotic sample to dispense into the peni cylinder www.omniconzonereader.com omni-noculator peni cylinder filler 15

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